Caracterización de andamios de seda fibroína electrohilados para ingeniería de tejidos óseo: una revisión

Palabras clave: Fibroína de seda, caracterización de electrospinning, ingeniería de tejidos óseo

Resumen

La fibroína de seda es un polímero natural obtenido del gusano Bombyx mori, que se ha utilizado en la ingeniería de tejidos óseos debido a sus propiedades de biocompatibilidad, adhesión, baja biodegradabilidad y resistencia a la tracción. El electrohilado es una técnica para desarrollar nanofibras, utiliza altos voltajes para convertir soluciones de polímeros en andamios nanoestructurados, con porosidad, buena relación entre el área superficial y el volumen. En esta revisión examinamos los parámetros de electrohilado en la morfología de la fibra, después del tratamiento de las fibras hiladas. Además, presentamos diferentes caracterizaciones fisicoquímicas de andamios de fibroína de seda electrohilada como morfológico (microscopia electrónica de barrido - SEM), estructura cristalina (espectroscopia de transformada infrarroja de Fourier - FTIR, difracción de rayos X- XRD), análisis térmico (calorimetría diferencial de barrido- DSC, análisis termogravimétrico - TGA) y propiedades mecánicas (resistencia a la tracción). Finalmente, presentamos una discusión concerniente a las potenciales aplicaciones e impactos de la fibroína de seda electrohilada en la ingeniería del tejido óseo y las tendencias futuras.

Biografía del autor/a

Mónica Liliana Mejía-Suaza*, Instituto Tecnológico Metropolitano, Colombia

MSc in Biomedical Engineering, Faculty of Engineering, Instituto Tecnológico Metropolitano, monicamejia2111@gmail.com

Maria Elena Moncada, Instituto Tecnológico Metropolitano, Colombia

PhD in Electrical Engineering, Faculty of Engineering, Instituto Tecnológico Metropolitano, mariamoncada@itm.edu.co

Claudia Patricia Ossa-Orozco , Universidad de Antioquia, Colombia

PhD in Metallurgical and Materials Engineering, Biomaterials Research Group, Bioengineering Program, Faculty of Engineering, Universidad de Antioquia, claudia.ossa@udea.edu.co

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Cómo citar
[1]
M. L. Mejía Suaza, M. E. Moncada, y C. P. . Ossa-Orozco, «Caracterización de andamios de seda fibroína electrohilados para ingeniería de tejidos óseo: una revisión», TecnoL., vol. 23, n.º 49, pp. 33–51, sep. 2020.

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Publicado
2020-09-15
Sección
Artículos de revisión

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