Advances in Research into Encapsulation through Ionic Gelation: A Systematic Review

Keywords: Sodium alginate, bioactive compounds, ionic gelation, wall material


Encapsulation, a technology that creates a barrier between a compound of interest and the environment, improves the physicochemical stability of products during processing and/or storage. Therefore, it helps to reduce the degradation of compounds of interest, masks undesirable odors and flavors, controls the release of the bioactive compound, and can increase its bioaccessibility and bioavailability. The objective of this review was to collect and discuss recent scientific literature about encapsulation by ionic gelation of bioactive compounds, microorganisms, and enzymes, as well as its use in different applications of scientific and/or industrial interest in several fields. A literature review was carried out in indexed databases using descriptors such as capsule size, encapsulation efficiency, mixture matrices, sodium alginate, and ionic gelation. The results show that using of this kind of encapsulation offers variable advantages regarding the bioavailability of bioactive compounds, the stability of different compounds, the improvement of physical characteristics, the release of compounds, and the protection against adverse environmental effects. In conclusion, the ionic gelation method can have a wide range of applications to encapsulate food ingredients, microorganisms, drugs, etc. This review can guide further research into ionic gelation because it examines the diversity of its applications.

Author Biographies

Nallely Ortiz-Romero, Tecnológico Nacional de México/I T de Durango, México

Tecnológico Nacional de México/I T de Durango, Durango-México,

Luz Araceli Ochoa-Martínez*, Tecnológico Nacional de México/I T de Durango, México

 Tecnológico Nacional de México/I T de Durango, Durango-México,

Silvia Marina González-Herrera, Tecnológico Nacional de México/I T de Durango, México

Tecnológico Nacional de México/I T de Durango, Durango-México,

Olga Miriam Rutiaga-Quiñones , Tecnológico Nacional de México/I T de Durango, México

Tecnológico Nacional de México/I T de Durango, Durango-México,

José Alberto Gallegos-Infante, Tecnológico Nacional de México/I T de Durango, México

Tecnológico Nacional de México/I T de Durango, Durango-México,


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How to Cite
N. Ortiz-Romero, L. A. Ochoa-Martínez, S. M. González-Herrera, O. M. Rutiaga-Quiñones, and J. A. Gallegos-Infante, “Advances in Research into Encapsulation through Ionic Gelation: A Systematic Review”, TecnoL., vol. 24, no. 52, p. e1962, Aug. 2021.


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