Morphological characterization of SARS-CoV-2 through electronic microscopy

Keywords: SARS-CoV-2, electron microscopy, morphology characterization, COVID-19


This paper reviews the available literature on the morphological characterization of the SARS-CoV-2 virus by electron microscopy. It presents the most relevant technical aspects for the preparation of samples used by various authors in the field because the details related to said preparation are decisive to obtain the images. In addition, it addresses biosecurity-related factors. Finally, the main morphological characteristics of the virus are described based on the images found in the literature. The morphology of the virus is characterized by a crown-like shape on its surface. Such crowns are composed of spikes and other proteins, forming layers on the surface that are used to penetrate and bind to host cells through the cell membrane.

Author Biographies

Robison Buitrago-Sierra*, Instituto Tecnológico Metropolitano, Colombia


Álvaro Guzmán , Instituto Tecnológico Metropolitano, Colombia
Juan Felipe Santa-Marín, Instituto Tecnológico Metropolitano, Colombia



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How to Cite
Buitrago-Sierra, R., Guzmán , Álvaro, & Santa-Marín, J. F. (2021). Morphological characterization of SARS-CoV-2 through electronic microscopy. TecnoLógicas, 24(50), e1675.


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